Invited Review Infectious Agents in Coronary Atheromas: a Possible Role in the Pathogenesis of Plaque Rupture and Acute Myocardial Infarction
نویسندگان
چکیده
Instituto do Coração (InCor) do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil. Correspondence to: Maria de Lourdes Higuchi, M.D., Laboratório de Anatomia Patológica, Instituto do Coração/InCor, Faculdade de Medicina da Universidade de São Paulo, Av. Dr. Enéas C. Aguiar 44, 05403-000 São Paulo, SP, Brasil. Tel: +55 11 30695252, FAX: +55 11 3069-5251. e-mail: [email protected] INVITED REVIEW
منابع مشابه
CD4⁺Foxp3⁺ Treg and its ICOS⁺ Subsets in Patients with Myocardial Infarction
Background: Atherosclerosis is a multifactorial disorder with chronic inflammatory conditions in which immune cells play a significant role in its pathogenic process. Regulatory T cells (Treg), as a part of immune system, are involved in controlling autoimmune and inflammatory diseases. Quantitative and/or functional alteration of Tregs has been shown to play an atheroprotective role and may al...
متن کاملThe Role of Low-Molecular Weight Heparins in Non-ST Elevation Myocardial Infarction
Non-ST elevation myocardial infarction (NSTEMI) is a subset clinical manifestation of acute coronary syndrome (ACS), which is usually caused by disruption of vulnerable atherosclerotic plaque, followed by thrombosis resulting various degree of occlusions in coronary arteries. The exposure of tissue factors following the plaque rupture causes activation of coagulation cascades and formation of f...
متن کاملCoronary disease BASIC ASPECTS OF PLAQUE VULNERABILITY
The treatment of acute coronary syndromes, including acute myocardial infarction and unstable angina, has been one of the most successful contributions in the last 20 years to the improvement of medicine. However, we are still unable to predict them, and therefore to prevent occurrence of acute myocardial infarction and/or death. Major improvements have been made in an effort to understand the ...
متن کامل[From vulnerable plaque to vulnerable patient].
Atherosclerotic plaque instability is directly involved in triggering acute coronary syndromes, including unstable angina, acute myocardial infarction, and sudden coronary death. Different and not completely unknown mechanisms are involved in the pathogenesis of the destabilisation of the vulnerable plaque; currently three mechanisms are considered to play a causal role in this process: emboliz...
متن کاملAnatomic - physiologic links between acute coronary syndromes RICHARD
THE BEST THERAPY for a given morbid condition is possible only when both its pathoanatomy and pathophysiology are clearly understood. This certainly applies to the acute ischemic syndromes of the heart. Early in the study of myocardial infarction the term was considered to be synonymous with acute coronary thrombosis." 2 This theory remained intact for many years, to be challenged only within t...
متن کامل